The Greek verb “ἐκλύω” – Limited to Mt. 9:36; 15:32; Mk. 8:3; Gal. 6:9; Heb. 12:3, 5,

the Greek verb “ekluo” meant “become despondent,” “weaken,” “have one’s strength relaxed,” “to be enfeebled through exhaustion,” “faint,” “be tired out.”  Hungry people had become weary and were about to faint (Mt. 15:32 and compare Mk. 8:3).  The saved are encouraged to not become “weary” in well-doing (Gal. 6:9).

A series of sermons – a few of which are listed below – could be preached in relation to “fatigue,” “being tired,” and “weariness.”  Here are some ideas from http://www.abiblecommentary.com/audiosermon

Psalm 44 (especially the final verses — 22 Yea, for thy sake are we killed all the day long; we are accounted as sheep for the slaughter.
23 Awake, why sleepest thou, O Lord? Arise, cast (us) not off for ever.
24 Wherefore hidest thou thy face, and forgettest our affliction and our oppression?  25 For our soul is bowed down to the dust: our body cleaveth unto the earth. 26 Rise up for our help, and redeem us for thy lovingkindness’ sake.

Weary doctors and weary Christians (part 1)

Weary doctors and weary Christians (part 2)

Physical weariness due to age